COLUL UTERIN NOTIUNI FUNDAMENTALE SI MODIFICARI IN SARCINA

COLUL UTERIN NOTIUNI FUNDAMENTALE SI MODIFICARI IN SARCINA

Stamatian F., Boitor-Borza D., Cruciat Gh.
Clinica Obstetrică-Ginecologie 1, Spitalul Clinic Judeţean Cluj, UMF Cluj Napoca

Rezumat

    Colul uterin este o structura unica, formata predominant dintr-o matrice extracelulara ce contine fibre de colagen. In timpul sarcinii si al nasterii, acesta sufera importante modificari morfologice si biochimice. Remodelarea colului este rezultatul unui metabolism activ care se gaseste sub controlul unor factori endocrini, paracrini si mecanici.

    Lucrarea noastra aduce in atentie principalele aspecte ale embriologiei, anatomiei si histologiei colului uterin, insistand asupra acelor notiuni care au aplicabilitate in studiul clinic al colului. In partea a doua realizam o trecere in revista a factorilor si a mecanismelor implicate in modificarile colului uterin in timpul sarcinii si al nasterii, cu referinte din literatura de actualitate.

Abstract – THE UTERINE CERVIX: FUNDAMENTAL KNOWLEDGE AND CHANGES DURING PREGNANCIES

     Uterine cervix is a unique structure composed mostly of collagen fibriles and extracellular matrix. During pregnancy and labor it undergoes important morphological and biochemical changes. Cervical remodeling is the consequence of an active metabolism which is regulated by endocrines, paracrines and mechanical factors.
    Our paper focuses on the main embryological, anatomical and histological aspects of the uterine cervix. We insist on the most important topics which are useful in the clinical study of the cervix. Then we make a review of the literature concerning the factors and the mechanisms implied in the cervical remodeling during pregnancy and parturition.

Key words: uterine cervix, embryology, anatomy, histology, cervical remodeling